The name "Digitek" is taken from the name "Digitalis", which is the scientific name for the " Foxglove", which includes digitalis purpurea (so called for its purple flowers) and digitalis lanata. Also known as "Dead Man's Bells or Witches' Gloves, it is one of the four best known deadly plant poisons, along with Hemlock, Belladona (Deadly Nightshade), and Wolfsbane (Monk's Hood). The entire plant is considered poisonous including the roots and the seeds, and especially the leaves of the upper stem, with just a small bite being enough to potentially cause death.
A group of pharmacologically active compounds including Digoxin and Digitoxin, are extracted mostly from the leaves of the second year's growth. Like many of today's drugs Digitalis was originally used as a folklorist and herbalist remedy. It's use was abandoned because of it's narrow theraputic index and the difficulty of determining exactly how much of the drug to use in herbal preparations.
Early symptoms of ingestion include nausea, vomiting, anorexia, diarrhea, abdominal pain, wild hallucinations, delirium, and severe headache. Depending on the severity of the toxicosis the victim may later suffer irregular and slow pulse, tremors, various cerebral disturbances, especially of a visual nature (unusual colour visions with objects appearing yellowish to green, and blue halos around lights), convulsions, and deadly disturbances of the heart.
Digitalis poisoning can cause heart block and bradycardia (lowered heart rate) and tachycardia (increased heart rate). It can cause either, depending on the dose and the condition of one's heart. It also has a vagal effect on the parasympathetic nervous system, and as such is used in reentrant cardiac arrhythmias and to slow the ventricular rate during atrial fibrillation. The dependence on the vagal effect means that digitalis is not effective when a patient has a high sympathetic nervous system drive, which is the case with acutely ill persons, and also during exercise.
